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LUTATHERA results 
 
 

Whether you've just been diagnosed or progressing while on somatostatin analogues (SSAs), LUTATHERA can help slow down neuroendocrine tumor (NET) progression

If you're looking for a first treatment after diagnosis, LUTATHERA can help slow NET progression

In a study of 226 patients with faster-growing NETs, LUTATHERA with an SSA was shown to reduce how fast tumors grew or spread for over a year longer than SSA treatment alone.* 

Half of the patients taking LUTATHERA with an SSA did not have their cancer grow or spread for 22.8 months compared with 8.5 months with an SSA alone, roughly 3x more time without their cancer getting worse.

The median progression-free survival was 22.8 months in patients who took LUTATHERA and an SSA, and 8.5 months in patients taking only an SSA roughly 3x more time without their cancer getting worse.

*~14 months longer time to progression with LUTATHERA + SSA.

With LUTATHERA, 4x more patients also saw their tumors shrink or disappear

More patients with faster-growing NETs saw their tumors shrink or disappear, also known as overall response, with LUTATHERA + SSA compared to SSA alone.

The overall response rate was 43% in patients who took LUTATHERA and an SSA, and 9% in patients taking only an SSA. Four times more patients saw their tumors shrink or disappear with LUTATHERA plus an SSA compared with an SSA alone.

This response lasted for ~2 years.

The overall response rate (ORR) is the percentage of patients whose cancer got smaller or disappeared.

The data are from the NETTER-2 trial, which included 226 patients who were recently diagnosed with SSTR+ NETs that were faster growing (Ki-67, 10%–55%). They were split into 2 groups: 151 received LUTATHERA and a long-acting SSA, and 75 received a long-acting, high-dose SSA alone.

 

Seperator

 

If your NETs have progressed on an SSA, LUTATHERA can delay NET progression for longer

In a study of 229 patients whose NETs progressed on an SSA alone, LUTATHERA + SSA helped delay tumors from growing or spreading by more than 2 years.

LUTATHERA + SSA provided more time without their cancer growing or spreading: 28.4 months compared with 8.5 months with an SSA alone, or more than 2 years without their cancer getting worse.

The median progression-free survival was 28.4 months in patients who took LUTATHERA and an SSA, and 8.5 months in patients taking only an SSA–more than 2 years without their cancer getting worse

 

3x more patients who had SSA treatment before saw their tumor shrink or disappear with LUTATHERA

More patients whose NETs had progressed on an SSA alone saw their tumors shrink or disappear, also known as overall response, with LUTATHERA + SSA compared to those taking an SSA alone. 

Bar chart showing the overall response rate was 13% in patients who took LUTATHERA and an SSA, and 4% in patients taking only an SSA. Three times more patients saw their tumors shrink or disappear with LUTATHERA plus an SSA compared with an SSA alone.

The data are from the NETTER-1 trial, which included 229 patients with SSTR+ NETs who had tumors that were slower growing (Ki-67, 0%–20%) and progressed on treatment with an SSA. They were split into 2 groups: 116 received LUTATHERA and a long-acting SSA, and 113 received a long-acting, high-dose SSA alone.

 

Hear from Donna, a real person treated with LUTATHERA

Donna's quote: I'm not just standing by and watching the world go by, Iˇm taking control of my life and LUTATHERA helped me get there. Donna, a real LUTATHERA patient.

Since her diagnosis, Donna and her husband Don’s lives have been changed by NETs. Listen as they tell their story of self-advocacy and strength rooted in the love of their family. Join in Donna’s strength and watch her journey as one of the 20,000+ patients treated with LUTATHERA.