Novartis Patient Support Line 1-844-638-7222, Monday-Friday, 8:00 AM - 8:00 PM ET, excluding holidays.
Treatment with LUTATHERA
LUTATHERA works by specifically targeting neuroendocrine tumors (NETs) to slow progression
LUTATHERA is a targeted therapy called peptide receptor radionuclide therapy (PRRT). PRRTs can target a specific protein on cancer cells.
LUTATHERA specifically targets proteins found on the surface of most NETs, called somatostatin receptors (SSTRs). By targeting these proteins, LUTATHERA delivers a powerful dose of radiation right to the cells.
This happens in 2 steps.
How LUTATHERA works
LUTATHERA finds NET cells by targeting the SSTRs on the surface of the cells.
LUTATHERA enters the NET cells and attacks from within. It releases radiation inside the cells, destroying them.
LUTATHERA targets and attacks cells that have SSTRs but radiation also affects neighboring cells.
9 of 10 patients with NETs are somatostatin receptor-positive (SSTR+). Know your status to see if LUTATHERA is right for you
How will I receive LUTATHERA?
LUTATHERA is an infusion given at your nearest treatment center.
Your doctor will send you to a treatment center that is trained specifically to give LUTATHERA.
There are over 440 LUTATHERA treatment sites across the United States.
LUTATHERA is given in 4 intravenous (IV) treatments, once every 8 weeks
You and your doctor will work together to decide on the best dosing plan for your cancer
- Between 4 to 24 hours after each dose of LUTATHERA, you'll get an intramuscular (IM) injection of long-acting somatostatin analogue (SSA)
- After your last dose of LUTATHERA, you may continue receiving long-acting SSA every 4 weeks for up to 18 months
Nearly 9 out of 10 patients with newly diagnosed NETs and almost 8 of 10 who were already on an SSA finished all 4 doses of LUTATHERA
LUTATHERA Patient Brochure
Reminders before, during, and after each LUTATHERA treatment
When starting LUTATHERA, knowing what to expect can help you feel prepared and ready for treatment.
What should I expect before each dose of LUTATHERA?
- Your doctor will stop your long-acting SSA treatment until your first LUTATHERA dose
- You may receive short-acting SSA to help with symptoms before you start LUTATHERA
- Your doctor will stop your short-acting SSA treatment at least 24 hours before each infusion
What should I expect on infusion day?
- You will be given a medicine to help with any nausea and vomiting that you may experience
- Thirty minutes before you are given LUTATHERA, you will start an amino acid infusion. This will help protect your kidneys
The total infusion time is ~4 to 5 hours
- LUTATHERA infusion takes 30 to 40 minutes
- You will continue the amino acid infusion for at least 3 hours after the LUTATHERA infusion to protect your kidneys
- Your care team will monitor you throughout the day
What does follow-up after my infusion look like?
- Your care team will tell you when and where you will receive a long-acting SSA
- Your care team will perform regular blood work and other tests to see how you are doing on treatment
- These tests can tell them if you are having side effects and will help them give you the care you need
Your care team will support you every step of the way
Contact them with any questions about laboratory appointments or your next LUTATHERA dose.